A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name rs507879
Type SNP
Species Homo sapiens
Tissue Blood
Experiment Method RT-PCR,other
Up/Down Down
Pro/Anti NA
Funtion Description An analysis of 510 subjects aged 75-103years revealed 205 (40%) CASP5 Ala90Thr heterozygotes as compared to 254 (50%) expected from the minor allele frequency 0.470 (p=0.000014). This deviation was not observed in 549 middle-aged (18-50years) controls (27
Regulation Gene CASP5
Year 2010
Pubmed ID 20434535
Title Evidence for depletion of CASP5 Ala90Thr heterozygous genotype in aged subjects.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant SNP
High-throughput NA