| Name |
rs646776
|
| Type |
SNP
|
| Species |
Homo sapiens
|
| Tissue |
Cardiovascular Disease in Utah Pedigrees Sample;Family Heart Study sample
|
| Experiment Method |
qPCR
|
| Up/Down |
NA
|
| Pro/Anti |
NA
|
| Funtion Description |
The rs646776 SNP at the SORT1 locus showed an age interaction that was significant in cross-sectional analyses of 1350 individuals from Utah (p = 0.0003) and in 2977 individuals from the NHLBI Family Heart Study (p = 0.007) as well as in longitudinal anal
|
| Regulation Gene |
SORT1
|
| Year |
2011
|
| Pubmed ID |
21466885
|
| Title |
Evaluation of the gene-age interactions in HDL cholesterol, LDL cholesterol, and triglyceride levels: the impact of the SORT1 polymorphism on LDL cholesterol levels is age dependent.
|
| Drug |
NA
|
| Disease |
NA
|
| Environment Factors |
NA
|
| Circulating |
NA
|
| Variant |
SNP
|
| High-throughput |
NA
|