A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name clk-1
Type gene
Species Caenorhabditis elegans
Tissue NA
Experiment Method other
Up/Down Down
Pro/Anti Pro
Funtion Description The discovery that reduced activity of the mitochondrial enzyme CLK-1/MCLK1 (also known as COQ7) extends lifespan in both Caenorhabditis elegans and mice
Regulation Gene NA
Year 2009
Pubmed ID 19478076
Title Reversal of the mitochondrial phenotype and slow development of oxidative biomarkers of aging in long-lived Mclk1+/- mice.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant 1
High-throughput NA