A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name TNF-a/-238G> A
Type SNP
Species Homo sapiens
Tissue Blood
Experiment Method RFLP-PCR,other
Up/Down NA
Pro/Anti NA
Funtion Description Single-locus analysis showed that only ADA 22G>A is significantly associated with human life-expectancy in males (comparison 1 (age class 2 vs. age class 1), O.R. 1.943, P=0.036; comparison 2 (age class 3 vs. age class 2), O.R. 0.320, P=0.0056). Age- and
Regulation Gene NA
Year 2011
Pubmed ID 21865054
Title Age- and gender-specific epistasis between ADA and TNF-a influences human life-expectancy.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant SNP
High-throughput NA