Details
| Name | TP53 |
| Type | SNP |
| Species | Homo sapiens |
| Tissue | NA |
| Experiment Method | other |
| Up/Down | Up |
| Pro/Anti | Anti |
| Funtion Description | A wellknown functional SNP in the tumor suppressor TP53 gene leads to increased longevity: in the Danish general population (n = 9219) homozygotes for the minor allele versus homozygotes for the major allele had an increase in median survival of 3 years. |
| Regulation Gene | NA |
| Year | 2008 |
| Pubmed ID | 18256523 |
| Title | The common germline Arg72Pro polymorphism of p53 and increased longevity in humans. |
| Drug | NA |
| Disease | NA |
| Environment Factors | NA |
| Circulating | NA |
| Variant | SNP |
| High-throughput | NA |