A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name WRN
Type SNP
Species Homo sapiens
Tissue Mexican Samples
Experiment Method qPCR
Up/Down Down
Pro/Anti Pro
Funtion Description Population studies of the 1074Leu/Phe and 1367Cys/Arg polymorphisms were undertaken to evaluate the role of WRN in atherogenesis. Frequencies of the 1074Leu/Phe polymorphisms in Finnish and Mexican populations revealed an age-dependent decline of 1074Phe/
Regulation Gene WRN
Year 2000
Pubmed ID 11186893
Title Polymorphisms at the Werner locus: II. 1074Leu/Phe, 1367Cys/Arg, longevity, and atherosclerosis.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant SNP
High-throughput NA