| Name |
Y402H
|
| Type |
SNP
|
| Species |
Homo sapiens
|
| Tissue |
blood samples
|
| Experiment Method |
qPCR
|
| Up/Down |
NA
|
| Pro/Anti |
Pro
|
| Funtion Description |
In individuals of European ancestry, there was a significant association between Y402H and late-age-related macular degeneration with a per-allele odds ratio (OR) of 2.27 [95% confidence interval (CI) 2.10-2.45; P = 1.1 x 10(-161)]. There was no evidence
|
| Regulation Gene |
CFH
|
| Year |
2012
|
| Pubmed ID |
22253316
|
| Title |
Complement factor H genetic variant and age-related macular degeneration: effect size, modifiers and relationship to disease subtype
|
| Drug |
NA
|
| Disease |
age-related macular degeneration
|
| Environment Factors |
NA
|
| Circulating |
1
|
| Variant |
SNP
|
| High-throughput |
NA
|