A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name Y402H
Type SNP
Species Homo sapiens
Tissue CNV membranestissue
Experiment Method qPCR
Up/Down NA
Pro/Anti Pro
Funtion Description BLD are composed of different complement factors (factor H, C3, C5b-9) and extracellular matrix proteins such as vitronectin. The prevalence of homozygous carriers in regard to CFH Y402H polymorphism, which is suspicious for AMD, might be associated with
Regulation Gene CFH
Year 2007
Pubmed ID 17704937
Title Complement factor H variant Y402H and basal laminar deposits in exudative age-related macular degeneration.
Drug NA
Disease AMD
Environment Factors NA
Circulating 1
Variant SNP
High-throughput NA