Details
| Name | C-MYC |
| Type | gene |
| Species | Homo sapiens |
| Tissue | HT-1080 |
| Experiment Method | PCR;Western blot |
| Up/Down | Up |
| Pro/Anti | Pro |
| Funtion Description | TIGAR prevents the intracellular accumulation of c-Myc-induced ROS and inhibits oncogeneinduced cellular senescence in ATL, acute lymphoblastic leukemia, and multiple myeloma cells with elevated cMyc expression. Our results allude to a pivotal role for p5 |
| Regulation Gene | NA |
| Year | 2018 |
| Pubmed ID | 29462755 |
| Title | The human T-cell leukemia virus type-1 p30II protein activates p53 and induces the TIGAR and suppresses oncogene-induced oxidative stress during viral carcinogenesis. |
| Drug | NA |
| Disease | ATL |
| Environment Factors | NA |
| Circulating | NA |
| Variant | NA |
| High-throughput | NA |