| Name |
TauAT
|
| Type |
somatic mutation
|
| Species |
Caenorhabditis elegans
|
| Tissue |
NA
|
| Experiment Method |
western blot
|
| Up/Down |
Up
|
| Pro/Anti |
Pro
|
| Funtion Description |
These results suggest that mutant Tau aggravates conditions such as excitotoxicity and enhanced aging related phenotypes
|
| Regulation Gene |
Tau
|
| Year |
2018
|
| Pubmed ID |
29894752
|
| Title |
Glutamatergic nervous system degeneration in a C. elegans TauA152T tauopathy model involves pathways of excitotoxicity and Ca2+ dysregulation.
|
| Drug |
NA
|
| Disease |
frontotemporal dementia-related disorders and Alzheimer disease
|
| Environment Factors |
NA
|
| Circulating |
NA
|
| Variant |
NA
|
| High-throughput |
NA
|