A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name 32W
Type somatic mutation
Species Homo sapiens
Tissue blood samples
Experiment Method qPCR
Up/Down NA
Pro/Anti Anti
Funtion Description The CFB variant 32W was associated with protection against neovascular age-related macular degeneration, compared to the common 32R variant (odds ratio 0.64, p<0.05, in logistic regression with CFB variants; odds ratio 0.53, p<0.05, in logistic regression
Regulation Gene CFB
Year 2011
Pubmed ID 21541267
Title Complement factor B polymorphism 32W protects against age-related macular degeneration
Drug NA
Disease age-related macular degeneration
Environment Factors NA
Circulating 1
Variant somatic mutation
High-throughput NA