Details
| Name | ACE |
| Type | somatic mutation |
| Species | Homo sapiens |
| Tissue | blood samples |
| Experiment Method | qPCR |
| Up/Down | NA |
| Pro/Anti | Pro |
| Funtion Description | A variant of ACE which predisposes to coronary heart disease is surprisingly more frequent in centenarians, with a significant increase of the homozygous genotype (p < 0.01). |
| Regulation Gene | ACE |
| Year | 1994 |
| Pubmed ID | 8136829 |
| Title | Genetic associations with human longevity at the APOE and ACE loci |
| Drug | NA |
| Disease | coronary heart disease |
| Environment Factors | NA |
| Circulating | 1 |
| Variant | somatic mutation |
| High-throughput | NA |