A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name Asn107Ile
Type somatic mutation
Species Homo sapiens
Tissue blood samples
Experiment Method qPCR
Up/Down NA
Pro/Anti Pro
Funtion Description The NPSR1 genotype significantly affected age at onset of the obsessive-compulsive disorder patients, with a mean age at onset approximately 4 yr earlier in homozygous carriers of the low-functioning Asn107 variant (rs324981) compared to patients with at
Regulation Gene NPSR1
Year 2013
Pubmed ID 23680103
Title The functional coding variant Asn107Ile of the neuropeptide S receptor gene (NPSR1) influences age at onset of obsessive-compulsive disorder
Drug NA
Disease obsessive-compulsive disorder
Environment Factors NA
Circulating 1
Variant somatic mutation
High-throughput NA