Details
| Name | ATM |
| Type | somatic mutation |
| Species | Mus musculus |
| Tissue | blood samples |
| Experiment Method | qPCR |
| Up/Down | NA |
| Pro/Anti | Pro |
| Funtion Description | The cerebella of ATM-/- mice appear normal by histologic examination at 3 to 4 months and the mice have no gross behavioral abnormalities. The majority of mutant mice rapidly develop thymic lymphomas and die before 4 months of age. These findings indicate |
| Regulation Gene | ATM |
| Year | 1996 |
| Pubmed ID | 8843194 |
| Title | Targeted disruption of ATM leads to growth retardation, chromosomal fragmentation during meiosis, immune defects, and thymic lymphoma. |
| Drug | NA |
| Disease | thymic lymphomas |
| Environment Factors | NA |
| Circulating | 1 |
| Variant | somatic mutation |
| High-throughput | NA |