A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name BRAF
Type somatic mutation
Species Homo sapiens
Tissue blood samples
Experiment Method qPCR
Up/Down NA
Pro/Anti NA
Funtion Description We show that BRAF-mutated melanomas occur in a younger age group on skin without marked solar elastosis and less frequently affect the head and neck area, compared to melanomas without BRAF mutations. The findings indicate that BRAF-mutated melanomas aris
Regulation Gene BRAF
Year 2011
Pubmed ID 21324100
Title BRAF mutations in cutaneous melanoma are independently associated with age, anatomic site of the primary tumor, and the degree of solar elastosis at the primary tumor site
Drug NA
Disease melanoma
Environment Factors NA
Circulating 1
Variant somatic mutation
High-throughput NA