| Name |
BRAF V600E
|
| Type |
somatic mutation
|
| Species |
Homo sapiens
|
| Tissue |
lung
|
| Experiment Method |
other
|
| Up/Down |
Up
|
| Pro/Anti |
Pro
|
| Funtion Description |
BRAF V600E mutation is frequently found in various types of benign tumors. For example, most acquired melanocytic nevi and a subset of colonic serrated polyps/adenomas have this mutation.And p16INK4a also contribute to the senescence caused by BRAF V600E.
|
| Regulation Gene |
NA
|
| Year |
2018
|
| Pubmed ID |
29312762
|
| Title |
Ciliated muconodular papillary tumor of the lung harboring BRAF V600E mutation and p16INK4a overexpression without proliferative activity may represent an example of oncogene-induced senescence.
|
| Drug |
NA
|
| Disease |
Ciliated muconodular papillary tumor (CMPT)
|
| Environment Factors |
NA
|
| Circulating |
NA
|
| Variant |
NA
|
| High-throughput |
NA
|