Details
| Name | CPEB |
| Type | gene |
| Species | Homo sapiens |
| Tissue | skin, lung |
| Experiment Method | PCR, Western blot |
| Up/Down | differential expression |
| Pro/Anti | NA |
| Funtion Description | Knockdown of CPEB causes skin and lung cells to bypass the M1 crisis stage of senescence; reintroduction of CPEB into the knockdown cells restores a senescence-like phenotype. Knockdown cells that have bypassed senescence undergo little telomere erosion. |
| Regulation Gene | NA |
| Year | 2008 |
| Pubmed ID | 19141477 |
| Title | CPEB regulation of human cellular senescence, energy metabolism, and p53 mRNA translation |
| Drug | 0 |
| Disease | NA |
| Environment Factors | oxidation |
| Circulating | NA |
| Variant | NA |
| High-throughput | NA |