Details
| Name | BRCA1 |
| Type | somatic mutation |
| Species | Mus musculus |
| Tissue | ovarian |
| Experiment Method | qRT-PCR,RNA interference,Immunohistochemistry and immunofluorescence |
| Up/Down | Up |
| Pro/Anti | Pro |
| Funtion Description | In Brca1-deficient mice, reproductive capacity was impaired, primordial follicle counts were lower, and DSBs(double-strand break) were increased in remaining follicles with age relative to wild-type mice. Furthermore, oocyte-specific knockdown of Brca1, M |
| Regulation Gene | NA |
| Year | 2013 |
| Pubmed ID | 23408054 |
| Title | Telomerase is required for zebrafish lifespan. |
| Drug | NA |
| Disease | NA |
| Environment Factors | NA |
| Circulating | NA |
| Variant | 1 |
| High-throughput | NA |