A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name c.709-1G>A
Type somatic mutation
Species Homo sapiens
Tissue blood samples
Experiment Method qPCR
Up/Down NA
Pro/Anti Pro
Funtion Description We calculated CTh maps in 13 asymptomatic carriers of the c.709-1G>A GRN mutation and 13 age- and sex-matched healthy subjects. Asymptomatic GRN mutation carriers presented different patterns of age-related cortical thinning in the right superior temporal
Regulation Gene GRN
Year 2013
Pubmed ID 23218900
Title Distinctive age-related temporal cortical thinning in asymptomatic granulin gene mutation carriers
Drug NA
Disease leukemogenesis
Environment Factors NA
Circulating 1
Variant somatic mutation
High-throughput NA