A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name C228T
Type somatic mutation
Species Homo sapiens
Tissue thyroid cancer cell lines
Experiment Method qPCR
Up/Down Up
Pro/Anti Pro
Funtion Description The TERT promoter was sequenced in 10 thyroid cancer cell lines and 144 tumors from 20 patients with anaplastic thyroid carcinoma (ATC), 51 with papillary thyroid carcinoma (PTC), 36 with follicular thyroid carcinoma (FTC), and 37 with medullary thyroid c
Regulation Gene TERT
Year 2014
Pubmed ID 24141777
Title The age- and shorter telomere-dependent TERT promoter mutation in follicular thyroid cell-derived carcinomas
Drug NA
Disease thyroid cancer
Environment Factors NA
Circulating NA
Variant somatic mutation
High-throughput NA