| Name |
C57BL
|
| Type |
somatic mutation
|
| Species |
Mus musculus
|
| Tissue |
kidney tissue,blood samples
|
| Experiment Method |
qPCR
|
| Up/Down |
NA
|
| Pro/Anti |
Pro
|
| Funtion Description |
We propose that high basal expression of Cyp24a1 makes C57BL/6 mice less sensitive to decreased Klotho expression and contributes to abrogation of Klotho-dependent aging-related phenotypes in B6-kl/kl mice.Noncoding variations in Cyp24a1 gene are associat
|
| Regulation Gene |
Cyp24a1
|
| Year |
2019
|
| Pubmed ID |
30920112
|
| Title |
Noncoding variations in Cyp24a1 gene are associated with Klotho-mediated aging phenotypes in different strains of mice
|
| Drug |
NA
|
| Disease |
NA
|
| Environment Factors |
NA
|
| Circulating |
1
|
| Variant |
somatic mutation
|
| High-throughput |
NA
|