Details
| Name | CDC13-EST2 |
| Type | somatic mutation |
| Species | Yeast |
| Tissue | Yeast strains and plasmids |
| Experiment Method | Southern blot |
| Up/Down | NA |
| Pro/Anti | Pro |
| Funtion Description | The expression of Cdc13-Est2 fusion protein resulted in overlong telomeres (2 to 4 folds longer than normal telomeres), and long telomeres were stably maintained during long-term chronological aging. Accordingly, genome instability, manifested by accumula |
| Regulation Gene | NA |
| Year | 2016 |
| Pubmed ID | 27855118 |
| Title | Tethering telomerase to telomeres increases genome instability and promotes chronological aging in yeast. |
| Drug | NA |
| Disease | NA |
| Environment Factors | NA |
| Circulating | NA |
| Variant | NA |
| High-throughput | NA |