A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name CETP
Type somatic mutation
Species Homo sapiens
Tissue Blood
Experiment Method other
Up/Down Up
Pro/Anti NA
Funtion Description High-density lipoprotein cholesterol (HDL-C) and cholesteryl ester transfer protein (CETP) gene deficiency mutations that increase HDL-C levels have been associated with exceptional longevity. Low HDL-C level is a risk factor for CVD mortality in elderly
Regulation Gene NA
Year 2008
Pubmed ID 19038839
Title A prospective study of high-density lipoprotein cholesterol, cholesteryl ester transfer protein gene variants, and healthy aging in very old Japanese-american men.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant 1
High-throughput NA