A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name CFHR1
Type somatic mutation
Species Homo sapiens
Tissue blood samples
Experiment Method qPCR
Up/Down NA
Pro/Anti NA
Funtion Description This study showed for the first time that a particular CFHR1 allotype, CFHR1*A, is strongly associated with age-related macular degeneration (odds ratio, 2.08; 95% confidence interval, 1.59-2.73; P<0.0001) and illustrate a peculiar genotype-phenotype corr
Regulation Gene CFHR1
Year 2012
Pubmed ID 22247456
Title Relevance of complement factor H-related 1 (CFHR1) genotypes in age-related macular degeneration
Drug NA
Disease age-related macular degeneration
Environment Factors NA
Circulating 1
Variant SNP
High-throughput NA