A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name CLK
Type somatic mutation
Species Caenorhabditis elegans
Tissue NA
Experiment Method SDS-PAGE
Up/Down NA
Pro/Anti Anti
Funtion Description Mutation in the Clk genes clk-1 and gro-1 mildly affect energy production, but repress energy consumption dramatically,thereby reducing the rate of anabolic metabolism and lengthening life span.
Regulation Gene clk-1
Year 2000
Pubmed ID 23604840
Title Patterns of metabolic activity during aging of the wild type and longevity mutants of Caenorhabditis elegans.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant mutation
High-throughput NA