A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name ClkAR
Type somatic mutation
Species Fly Strains
Tissue Flies
Experiment Method Immunohistochemistry;ROS measurement;RNA interference
Up/Down NA
Pro/Anti Anti
Funtion Description lifespan was similarly reduced in three arrhythmic mutants (ClkAR, cyc0 and tim0) and in wild-type flies under constant light, which stops the clock. In contrast, ClkAR mutants showed significantly faster age-related locomotor deficits (as monitored by st
Regulation Gene NA
Year 2017
Pubmed ID 28072817
Title Drosophila Clock Is Required in Brain Pacemaker Neurons to Prevent Premature Locomotor Aging Independently of Its Circadian Function
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA