A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name CLOCK
Type somatic mutation
Species Mus musculus
Tissue liver and muscle tissue
Experiment Method qPCR,Western blot
Up/Down NA
Pro/Anti Pro
Funtion Description At the same time, Clock mutant mice respond to low-dose irradiation by accelerating their aging program, and develop phenotypes that are reminiscent of those in Bmal2-deficient mice. Taken together, our results demonstrate the dichotomy in biological cons
Regulation Gene CLOCK
Year 2009
Pubmed ID 18418054
Title Disruption of the circadian clock due to the Clock mutation has discrete effects on aging and carcinogenesis
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA