A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name Cryba2
Type somatic mutation
Species Mus musculus
Tissue mice samples
Experiment Method qPCR
Up/Down NA
Pro/Anti NA
Funtion Description A new mutant characterized by a clear, but significantly smaller lens without any changes for cornea thickness, anterior chamber depth, or aqueous humor size, was identified. The smaller size of the lens was more pronounced in the homozygous mutants, whic
Regulation Gene Cryba2
Year 2011
Pubmed ID 21212184
Title First mutation in the BA2-crystallin encoding gene is associated with small lenses and age-related cataracts
Drug NA
Disease age-related cataract
Environment Factors NA
Circulating NA
Variant somatic mutation
High-throughput NA