A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name Cyt-1
Type somatic mutation
Species Caenorhabditis elegans
Tissue NA
Experiment Method Western Blot Analysis
Up/Down NA
Pro/Anti Pro
Funtion Description Mutants are hypersensitive to oxidative stress and age precociously in part because of increased superoxide anion production.
Regulation Gene Cyt-1
Year 2003
Pubmed ID 12672828
Title A complex II defect affects mitochondrial structure, leading to ced-3- and ced-4-dependent apoptosis and aging.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant somatic mutation
High-throughput NA