A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name Cyt-1
Type somatic mutation
Species Caenorhabditis elegans
Tissue NA
Experiment Method other
Up/Down Up
Pro/Anti Pro
Funtion Description These data suggest that CYT-1 directly participates in electron transport from FADH2 to coenzyme Q. Moreover, mutational inactivation of this process renders animals susceptible to oxidative stress and, as a result, leads to premature aging.
Regulation Gene cyt-1
Year 2000
Pubmed ID 11237107
Title Oxidative stress and aging in Caenorhabditis elegans.
Drug NA
Disease NA
Environment Factors elevated oxygen levels
Circulating NA
Variant somatic mutation
High-throughput NA