A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name DAF-16
Type somatic mutation
Species Caenorhabditis elegans
Tissue C. elegans strains
Experiment Method NA
Up/Down NA
Pro/Anti Anti
Funtion Description We have found that mutations in the gene daf-2 can cause fertile, active, adult Caenorhabditis elegans hermaphrodites to live more than twice as long as wild type. This lifespan extension, the largest yet reported in any organism, requires the activity of
Regulation Gene daf-16
Year 1993
Pubmed ID 8247153
Title A C. elegans mutant that lives twice as long as wild type.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant somatic mutation
High-throughput NA