| Name |
CSIG
|
| Type |
gene
|
| Species |
Homo sapiens
|
| Tissue |
kidney, brain
|
| Experiment Method |
PCR, Luciferase reporter assay, Western blot, Immunofluorescence, pulldown assay
|
| Up/Down |
Up
|
| Pro/Anti |
Anti
|
| Funtion Description |
Moreover, overexpression of CSIG significantly delayed the progression of replicative senescence, while knockdown of CSIG expression accelerated replicative senescence. Knockdown of PTEN diminished the effect of CSIG on cellular senescence.
|
| Regulation Gene |
NA
|
| Year |
2008
|
| Pubmed ID |
18678645
|
| Title |
CSIG Inhibits PTEN Translation in Replicative Senescence
|
| Drug |
0
|
| Disease |
glioblastoma
|
| Environment Factors |
NA
|
| Circulating |
NA
|
| Variant |
NA
|
| High-throughput |
NA
|