A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name DAF-16
Type somatic mutation
Species Caenorhabditis elegans
Tissue C. elegans strains
Experiment Method qPCR
Up/Down NA
Pro/Anti Pro
Funtion Description Here we show that null mutations in daf-16 suppress the effects of mutations in daf-2 or age-1; lack of daf-16 bypasses the need for this insulin receptor-like signalling pathway.
Regulation Gene DAF-16
Year 1997
Pubmed ID 9353126
Title The Fork head transcription factor DAF-16 transduces insulin-like metabolic and longevity signals in C. elegans.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant somatic mutation
High-throughput NA