A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name DAF-18
Type somatic mutation
Species Caenorhabditis elegans
Tissue NA
Experiment Method Lifespan Assay
Up/Down Up
Pro/Anti Pro
Funtion Description In addition, daf-18(nr2037) dramatically shortens lifespan, both in a wild-type background and in a daf-2 mutant background that normally prolongs lifespan.
Regulation Gene daf-18
Year 1999
Pubmed ID 10377431
Title The PTEN tumor suppressor homolog in Caenorhabditis elegans regulates longevity and dauer formation in an insulin receptor-like signaling pathway.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA