A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name DAF-2
Type somatic mutation
Species Caenorhabditis elegans
Tissue C. elegans strains
Experiment Method qPCR
Up/Down NA
Pro/Anti Anti
Funtion Description In contrast, mutants with reduced activity of the gene daf-2, a homolog of the insulin and insulin-like growth factor receptors, age more slowly than normal and live more than twice as long.
Regulation Gene daf-2
Year 1997
Pubmed ID 9360933
Title daf-16: An HNF-3/forkhead family member that can function to double the life-span of Caenorhabditis elegans.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant somatic mutation
High-throughput NA