A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name DAF-2
Type somatic mutation
Species Caenorhabditis elegans
Tissue C. elegans strains
Experiment Method qPCR
Up/Down NA
Pro/Anti Anti
Funtion Description In this study, we demonstrated that the daf-2 mutation also conferred an oxidative stress resistance (Oxr) phenotype, which was also enhanced by the clk-1 mutation. Similar to the Age phenotype, the Oxr phenotype was regulated by the genetic pathway of in
Regulation Gene daf-2
Year 1999
Pubmed ID 10428762
Title The daf-2 gene network for longevity regulates oxidative stress resistance and Mn-superoxide dismutase gene expression in Caenorhabditis elegans.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant somatic mutation
High-throughput NA