A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name dna2
Type somatic mutation
Species Yeast
Tissue yeast strains
Experiment Method qPCR;ChIP
Up/Down NA
Pro/Anti Pro
Funtion Description dna2 mutants do have severely shortened life spans. We observed a variety of mutants, including the temperature-sensitive dna2-1 mutant, at a permissive temperature, and dna2-20 and dna2-21, which require osmotic support (19). We also used dna2-2, which i
Regulation Gene dna2
Year 2002
Pubmed ID 12024027
Title Mutations in DNA Replication Genes Reduce Yeast Life Span
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant somatic mutation
High-throughput NA