A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name EBP
Type somatic mutation
Species Mus musculus
Tissue liver
Experiment Method Southwestern Blot
Up/Down Up
Pro/Anti Pro
Funtion Description We find that nuclear extracts from normal aged mouse livers have decreased p42(C/EBPalpha) levels and binding activity, whereas those of p20(C/EBPalpha) and p20(C/EBPbeta) are increased. However, translation of 42-kDa C/EBPalpha is not down-regulated on p
Regulation Gene EBP
Year 1998
Pubmed ID 9614188
Title Effects of age on the posttranscriptional regulation of CCAAT/enhancer binding protein alpha and CCAAT/enhancer binding protein beta isoform synthesis in control and LPS-treated livers.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA