A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name ex-1 of CRYAA
Type somatic mutation
Species Homo sapiens
Tissue blood samples
Experiment Method qPCR
Up/Down NA
Pro/Anti Pro
Funtion Description The GA heterozygotes were at higher risk for developing NC and CC types of cataracts, where as the GG homozygotes for MT and AA homozygotes for PSC types were at risk. To our knowledge, an association of G>A transition found in ex-1 of CRYAA gene with ARC
Regulation Gene CRYAA
Year 2010
Pubmed ID 20606865
Title Association of G>A transition in exon-1 of alpha crystallin gene in age-related cataracts
Drug NA
Disease ARC
Environment Factors NA
Circulating 1
Variant somatic mutation
High-throughput NA