Details
| Name | GK138 |
| Type | somatic mutation |
| Species | Caenorhabditis elegans |
| Tissue | C. elegans strains |
| Experiment Method | RNAi |
| Up/Down | NA |
| Pro/Anti | Anti |
| Funtion Description | These results indicate that the life span-extending effect of the cep-1 mutation is mediated by autophagy. These results lend support to the hypothesis that autophagy has a broad positive impact on organismal aging. |
| Regulation Gene | cep-1 |
| Year | 2008 |
| Pubmed ID | 18728385 |
| Title | The effects of p53 on whole organism longevity are mediated by autophagy. |
| Drug | NA |
| Disease | NA |
| Environment Factors | NA |
| Circulating | NA |
| Variant | somatic mutation |
| High-throughput | NA |