Details
| Name | Gly1057(Asp/Asp) |
| Type | somatic mutation |
| Species | Homo sapiens |
| Tissue | Blood |
| Experiment Method | PCR,other |
| Up/Down | Up |
| Pro/Anti | Anti |
| Funtion Description | In the whole population, homozygous IRS2(Asp/Asp) participants were more represented among long lived(LL) versus control(C) participants (16.7% vs 12.0%; p = .04). And IRS2(Asp/Asp) participants were more likely to reach extreme old age (>or=90 percentile |
| Regulation Gene | IRS2 |
| Year | 2010 |
| Pubmed ID | 19887537 |
| Title | The IRS2 Gly1057Asp variant is associated with human longevity. |
| Drug | NA |
| Disease | NA |
| Environment Factors | NA |
| Circulating | NA |
| Variant | 1 |
| High-throughput | NA |