Details
| Name | DAF-16 |
| Type | somatic mutation |
| Species | Caenorhabditis elegans |
| Tissue | C. elegans strain |
| Experiment Method | qRT-PCR;RNAi |
| Up/Down | NA |
| Pro/Anti | Pro |
| Funtion Description | Mutation of daf-2, age-1, akt-1, or akt-2 gene induced a resistant property of nematodes to GO toxicity, while mutation of daf-16 gene led to a susceptible property of nematodes to GO toxicity, suggesting that GO may dysregulate the functions of DAF-2/IGF |
| Regulation Gene | NA |
| Year | 2016 |
| Pubmed ID | 27040644 |
| Title | Intestinal Insulin Signaling Encodes Two Different Molecular Mechanisms for the Shortened Longevity Induced by Graphene Oxide in Caenorhabditis elegans. |
| Drug | NA |
| Disease | NA |
| Environment Factors | NA |
| Circulating | NA |
| Variant | NA |
| High-throughput | NA |