A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name hCAP-H2
Type somatic mutation
Species Homo sapiens
Tissue RPE-1 cells (ATCC); HeLa, HCT116, and U2OS cells;PEO-1, OVCAR5, OVCAR10, and SKOV3 cells;HOSE4 cells
Experiment Method Fractionation;Western blotting;Immunoprecipitation;Immunofluorescence;RT-PCR and qRT-PCR
Up/Down NA
Pro/Anti Pro
Funtion Description Here, we show that the hCAP-H2 subunit of the condensin II complex exists as either a full-length protein or an N-terminus truncated variant ( delta N). While the full-length hCAP-H2 associates with mitotic chromosomes, the delta N variant exists as an i
Regulation Gene NA
Year 2015
Pubmed ID 26017022
Title A novel role for the condensin II complex in cellular senescence.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA