A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name HLA-A
Type somatic mutation
Species Homo sapiens
Tissue NA
Experiment Method Southern blotting
Up/Down Up
Pro/Anti Pro
Funtion Description Results of 167 assays in 73 individuals showed that the total number of mutant lymphocytes increased significantly with age from a geometric mean frequency of 0.71 x 10(-5) in neonates to 6.53 x 10(-5) in elderly individuals.
Regulation Gene HLA-A
Year 1992
Pubmed ID 1373828
Title In vivo human somatic mutation: frequency and spectrum with age.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA