Details
| Name | HPRT |
| Type | somatic mutation |
| Species | Rat Rattus |
| Tissue | spleen |
| Experiment Method | RT-PCR |
| Up/Down | Down |
| Pro/Anti | Anti |
| Funtion Description | The results indicate that CR reduces the accumulation of spontaneous somatic cell mutation in aging rats, especially those caused by base substitutions and frameshifts. |
| Regulation Gene | Hprt |
| Year | 2003 |
| Pubmed ID | 12787914 |
| Title | Effect of caloric restriction on Hprt lymphocyte mutation in aging rats. |
| Drug | NA |
| Disease | NA |
| Environment Factors | Caloric restriction |
| Circulating | NA |
| Variant | somatic mutation |
| High-throughput | NA |