Details
| Name | HPRT |
| Type | somatic mutation |
| Species | Mus musculus |
| Tissue | NA |
| Experiment Method | PCR |
| Up/Down | Up |
| Pro/Anti | Pro |
| Funtion Description | Dietary restriction, which prolongs life span, results in slowed accumulation of HPRT mutants in mice. Conversely,senescence-accelerated mice, which have been bred to have a shortened life span,show accelerated accumulation of somatic mutations. |
| Regulation Gene | HPRT |
| Year | 1998 |
| Pubmed ID | 9928416 |
| Title | Somatic mutation and aging. |
| Drug | NA |
| Disease | NA |
| Environment Factors | NA |
| Circulating | NA |
| Variant | NA |
| High-throughput | NA |