Details
| Name | INGla |
| Type | somatic mutation |
| Species | Homo sapiens |
| Tissue | NA |
| Experiment Method | qPCR,Western blot |
| Up/Down | Up |
| Pro/Anti | Pro |
| Funtion Description | Alternative splicing of the ING1 message alters the INGla:INGlb ratio by ~30-fold in senescent compared to low passage primary fibroblasts. INGla antagonizes INGlb function in apoptosis, induces the formation of structures resembling senescence-associated |
| Regulation Gene | ING1 |
| Year | 2008 |
| Pubmed ID | 18691180 |
| Title | ING1a expression increases during replicative senescence and induces a senescent phenotype |
| Drug | NA |
| Disease | NA |
| Environment Factors | NA |
| Circulating | NA |
| Variant | NA |
| High-throughput | NA |