| Name |
lamin A
|
| Type |
somatic mutation
|
| Species |
Homo sapiens
|
| Tissue |
vascular
|
| Experiment Method |
Western blot
|
| Up/Down |
NA
|
| Pro/Anti |
NA
|
| Funtion Description |
skin biopsy sections from a subject with HGPS showed that the truncated lamin A accumulates primarily in the nuclei of vascular cells.
|
| Regulation Gene |
NA
|
| Year |
2006
|
| Pubmed ID |
16461887
|
| Title |
Hutchinson-Gilford progeria mutant lamin A primarily targets human vascular cells as detected by an anti-Lamin A G608G antibody.
|
| Drug |
NA
|
| Disease |
Hutchinson-Gilford progeria syndrome
|
| Environment Factors |
NA
|
| Circulating |
NA
|
| Variant |
somatic mutation
|
| High-throughput |
NA
|