Details
| Name | LMNA |
| Type | somatic mutation |
| Species | Homo sapiens |
| Tissue | NA |
| Experiment Method | RT-PCR,other |
| Up/Down | Up |
| Pro/Anti | Pro |
| Funtion Description | A point mutation in lamin A (LMNA) gene, resulting in the production of a truncated protein product-progerin. WS is caused by mutations in WRN gene, encoding a loss-of function RecQ DNA helicase.Both HGPS and WS patients present a wide range of aging-asso |
| Regulation Gene | NA |
| Year | 2018 |
| Pubmed ID | 29476423 |
| Title | Differential stem cell aging kinetics in Hutchinson-Gilford progeria syndrome and Werner syndrome. |
| Drug | NA |
| Disease | Hutchinson-Gilford progeria syndrome |
| Environment Factors | UV irradiation |
| Circulating | 1 |
| Variant | 1 |
| High-throughput | NA |