Details
| Name | LMNA |
| Type | somatic mutation |
| Species | Homo sapiens |
| Tissue | HeLa |
| Experiment Method | other |
| Up/Down | NA |
| Pro/Anti | Pro |
| Funtion Description | Mutations in the gene encoding nuclear lamin A (LA) cause the premature aging disease Hutchinson-Gilford Progeria Syndrome. The most common of these mutations results in the expression of a mutant LA, with a 50-aa deletion within its C terminus. In this s |
| Regulation Gene | NA |
| Year | 2007 |
| Pubmed ID | 17360326 |
| Title | Alterations in mitosis and cell cycle progression caused by a mutant lamin A known to accelerate human aging. |
| Drug | NA |
| Disease | NA |
| Environment Factors | NA |
| Circulating | NA |
| Variant | 1 |
| High-throughput | NA |